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1. Chebulagic acid
   Inhibits the absorption of carbohydrates as a reversible and non-competitive potent alpha-glucosidase inhibitor.
2. Alpha-cyperone
   modulates the intestinal motility and minimizes the hunger pangs.[5] . Mobilizes the deposited fat from adipose tissue by its lipolytic action on B3-AR adenoreceptor.
3. Cumin aldehydestrong lipase inhibitor and suppresses the ingested fat absorption.Clinically proved for reduced serum levels of fasting cholesterol, triglyceride, and LDL and increased HDL.
4. B-glucogallin
   Inhibits the human aldose reductase enzyme with an IC50 of 17µM which is biologically relevant . Stimulates insulin sensitivity in adipocytes by increasing glucose
   uptake.
5. Emblicanin A&B
   Inhibits enzymes of carbohydrate absorption, including α-glucosidase (IC50 of 1.0µg/mL) and α-amylase (IC50 of 94.3µg/mL)

A Randomized Double-Blind Placebo-Controlled Clinical Trial.

Effect of cumin cyminum L. (Cumin aldehyde) intake on Weight Loss, Metabolic Profiles and Biomarkers of Oxidative Stress in Overweight Subjects:

Ann NutrMetab 2015; 66(2-3):117-124.